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New approaches might help Defeat HIVDrug resistance remains a major problem in the fight against HIV infection, but a different approach to drug development might be the answer.This viral inhibitors targeting the HIV – 1 protease function by a competitive mechanism. Writing in the BJ ChemBio Knowledge Environment of the Biochemical Journal, suggest Max Chang and colleagues at the Scripps Research Institute, La Jolla, that pharmaceutical companies with connections that could use an non-competitive allosteric mechanism of inhibition.

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