The results were published today in Research Translational Medicine.

Individuals with relapsed B-ALL have few treatment options; only 30 % react to salvage chemotherapy. Without a effective bone marrow transplant, few have any wish of long-term survival. In the current study, 16 patients with relapsed B-ALL were given an infusion of their very own genetically modified immune cells, known as T cells. The cells had been reeducated to recognize and destroy malignancy cells which contain the proteins CD19. As the overall full response rate for all sufferers was 88 %, also those with detectable disease prior to treatment had a complete response rate of 78 %, far exceeding the complete response rate of salvage chemotherapy alone.Regarding to Holliday, ‘Nearly 40 % of kids had a cotinine concentration above 0.17ng/ml, a level associated with lung dysfunction, and almost six % of children had salivary cotinine concentrations greater than those of nonsmoking Scottish bar workers before the introduction of very similar legislation in Scotland’.

Antibodies produced in space less effective than those produced on terra firma New research in the FASEB Journal shows that flawed antibody production may potentially compromise resistance to infections during long-term missions and jeopardize the outcome of an area missionThe visit to Mars just got a little more difficult given that French researchers can see that antibodies utilized to fight away disease might become seriously compromised during long-term space flight.