They now report that Otoferlin activity in the cochlea occurs only in the inner hair cells.

They also found, binds calcium and with other proteins known to interact play a role in neurotransmitter release. To further investigate the role of gene in a living animal, the researchers studied ‘knockout’mice completely lacking a functional gene Otoferlin. Is exposed to sounds of different frequencies, the mice showed no detectable activity in parts of the brain that normally process sound. – Flow you further noted that the deaf mice suffered a complete loss of neurotransmitter release from their inner hair cells, despite an apparently normal ‘ribbon synapse ‘and calcium.. They now report that Otoferlin activity in the cochlea occurs only in the inner hair cells, where it concentrates in the ribbon-associated synaptic vesicles.

While the outer hair cell defects hearing loss hearing loss can, she added, a loss of inner ear hair cells results in total deafness news more than news.UroToday – the only urological Web site having original content of by global urology key opinion leaders wrote written clinical practices.